USE OF DIRECT THROMBIN INHIBITORS FOR TREATING NON-ST-SEGMENT ELEVATION ACUTE CORONARY SYNDROMES IN SPECIAL PATIENT GROUPS: WOMEN, DIABETICS, THE ELDERLY, AND CHRONIC RENAL INSUFFICIENCY

USE OF DIRECT THROMBIN INHIBITORS FOR TREATING NON-ST-SEGMENT ELEVATION ACUTE CORONARY SYNDROMES IN SPECIAL PATIENT GROUPS: WOMEN, DIABETICS, THE ELDERLY, AND CHRONIC RENAL INSUFFICIENCY

This complimentary newsletter provides a targeted review of the results of the ACUITY trial with particular emphasis on the high risk populations - women, elderly, diabetics, and patients with chronic renal insufficiency. In addition, he describes the findings of ACUITY in relation to therapy "switch", when patients were initially treated with heparins prior to randomization. Emergency physicians are increasingly becoming exposed to a greater variety of therapies for patients with acute coronary syndrome. It is our hope to provide you, the practicing clinician, with the educational tools to continue to give outstanding care to your patients.

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DIRECT THROMBIN INHIBITORS IN NON-ST-SEGMENT ELEVATION ACUTE CORONARY SYNDROMES

DIRECT THROMBIN INHIBITORS IN NON-ST-SEGMENT ELEVATION ACUTE CORONARY SYNDROMES

For patients with non-ST-segment elevation acute coronary syndrome (NSTE ACS) presenting to the emergency department, appropriate anti-thrombotic and anti-platelet therapy is critical to optimize outcome. Unfractionated heparin is often given as an anti-thrombin in this setting, however, if suffers from a number of pharmacologic limitations including non-specific binding, the requirement for frequent monitoring of its anti-coagulant effect, and the formation of antibodies to the heparin/platelet factor 4/platelet complex which can cause heparin-induced thrombocytopenia (HIT) or heparin-induced thrombocytopenia thrombosis syndrome (HITTS). Low molecular weight heparins, also an indirect thrombin inhibitor, can be used without monitoring their anti-thrombin effects. Ease of use and effectiveness makes them a popular choice in the emergency setting.

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ADVANCING THE STANDARD OF CARE - CARDIOVASCULAR AND NEUROVASCULAR EMERGENCIES (2006)

ADVANCING THE STANDARD OF CARE - CARDIOVASCULAR AND NEUROVASCULAR EMERGENCIES (2006)

EMCREG–International is pleased to present this complimentary 84-page CME monograph covering the proceedings of our satellite symposium at the ACEP Scientific Assembly in New Orleans, Louisiana. A number of important topics are covered in this monograph including management of non-ST-segment elevation and ST-segment elevation acute coronary syndrome (ACS), the CRUSADE Quality Improvement Initiative, decreasing time to treatment for ST-segment elevation myocardial infarction, direct thrombin inhibitors in ACS, acute decompensated heart failure care, the use of lactate as a marker for trauma and sepsis, point-of-care testing for cardiac biomarkers, the management of hypertension in acute neurovascular emergencies and advances in acute stroke care.

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