Emergency Medicine Cardiac Research and Education Group
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CRUSADE National Quality Improvement Initiative

CRUSADE, a national quality improvement initiative, is designed to increase the practice of evidenced-based medicine for patients with diagnosed non-ST-segment-elevation acute coronary syndromes (NSTE ACS).

CRUSADE will use as its "gold standard", the NSTE ACS clinical practice guidelines developed by the American College of Cardiology (ACC) and the American Heart Association (AHA). Feedback to clinicians about care patterns and educational interventions will be used as strategies to improve the standard of care.

CRUSADE should raise physician awareness of and increase the application of the ACC/AHA guidelines for care of patients with acute coronary syndromes. Patients will benefit from this project.

For more information visit the CRUSADE website or send an email.


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15 May 2008
Cardiac troponin predicts acute decompensated heart failure mortality
A recent NEJM article reports that cardiac troponin elevation is associated with increased in-hospital mortality in patients with acute decompensated heart failure
15 May 2008
Multiple biomarkers can predict cardiovascular death risk
Research suggestes that the use of multiple biomarkers of renal and cardiovascular abnormalities improves cardiovascular disease risk stratification.
13 May 2008
Vulnerable patients have longer delays in STEMI presentation
A study reports that STEMI patients with combined factors such as older age, female gender, Hispanic or Black race, and diabetes have much longer delays in STEMI presentation.
12 May 2008
Bivalirudin switch reduces ACS bleeding risk
Bleeding risk cut in half in ACS patients by switching from unfractionated heparin or low molecular weight heparin to bivalirudin.
9 May 2008
Cardiac troponin-based MI diagnosis supported
Researchers report that the additional patients diagnosed with MI rather than UA since the definition of MI was redefined have an even higher long-term mortality.
9 May 2008
Discrepancies between ACC-AHA and ESC anticoagulant guidelines are being criticized
Experts suggest that discrepancies in recommendations for optimal anticoagulation treatment in updated US and European ACS management guidelines are confusing for clinicians.
8 May 2008
Combination of A- and B-type natriuretic peptide provide additional AMI prognostic information
Researchers report that "midregional" pro-atrial natriuretic peptide is a strong predictor of adverse outcome after AMI, and gives complementary information when combined with measurement of the prohormone of BNP.
7 May 2008
Portable ultrasound device offers effective PE triage
A study reports effective triage using a portable ultrasound device that can accurately screen emergency department patients with dyspnea for venous thromboembolism.
1 May 2008
Transient STEMI management proposed: immediate and intense
Researchers in Israel propose that patients with transient ST-elevation myocardial infarction (TSTEMI) may benefit from immediate, intense medical therapy and an early invasive approach.
28 April 2008
Serial NT-proBNP better than clinical assessment in predicting HF prognosis
Research suggests that monitoring levels of NT-proBNP is better than clinical assessment at predicting outcome in heart failure outpatients.
25 April 2008
Point-of-care D-dimer assay rules out VTE
Researchers test a new 15-minute rapid point-of-care D-dimer assay with diagnostic performance comparable to conventional laboratory D-dimer tests.
24 April 2008
Bivalirudin monotherapy optimal for diabetic ACS patients
The ACUITY data suggests ACS patients with diabetes are likely to have more ischemia and bleeding than other patients, but these adverse events can be minimized by bilvalirudin monotherapy
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