Emergency Medicine Cardiac Research and Education Group





CRUSADE National Quality Improvement Initiative

CRUSADE, a national quality improvement initiative, is designed to increase the practice of evidenced-based medicine for patients with diagnosed non-ST-segment-elevation acute coronary syndromes (NSTE ACS).

CRUSADE will use as its "gold standard", the NSTE ACS clinical practice guidelines developed by the American College of Cardiology (ACC) and the American Heart Association (AHA). Feedback to clinicians about care patterns and educational interventions will be used as strategies to improve the standard of care.

CRUSADE should raise physician awareness of and increase the application of the ACC/AHA guidelines for care of patients with acute coronary syndromes. Patients will benefit from this project.

For more information visit the CRUSADE website or send an email.


ADVANCING THE STANDARD of CARE: CARDIOVASCULAR and NEUROVASCULAR EMERGENCIES
Follow-up Monograph from the ACEP 2006 Symposium
(New Orleans, LA ACEP Scientific Assembly)

Want to see it Live? View the web cast!

Complete Monograph (6.0 MB): download here

Request a hardcopy Here!

  1. Introduction and Table of Contents

  2. Management of non-ST-segment Elevation Acute Coronary Syndrome (NSTE-ACS) in the ED: State-of-the-Art Anti-platelet Management
    (James W. Hoekstra, MD)    

  3. Non-ST-segment Elevation Acute Coronary Syndrome: Optimal Anti-Coagulant Therapy for the Emergency Department
    (Charles V. Pollack, MD)    

  4. CRUSADE Quality Improvement Initiative: Better Care for Patients with Unstable Angina and non-ST-segment Elevation Myocardial Infarction
    (Deborah D. Diercks, MD)    

  5. ST-segment Elevation Myocardial Infarction (STEMI): Decreasing the Time to Treatment in the ED
    (W. Brian Gibler, MD)    

  6. Novel Anti-thrombotic Therapies for Acute Coronary Syndrome: Direct Thrombin Inhibitors
    (Judd E. Hollander, MD)    

  7. Management of ST-segment Elevation Myocardial Infarction in the ED: State-of-the-Art Anti-platelet and Anti-thrombotic Therapy
    (James W. Hoekstra, MD)    

  8. Acute Decompensated Heart Failure: Novel Approaches to Classification and Treatment
    (J. Douglas Kirk, MD)    

  9. Lactate – A Marker for Sepsis and Trauma
    (Andra L. Blomkalns, MD)    

  10. Point-of-Care Testing for Cardiac Biomarkers in the ED: A Blueprint for Implementation
    (W. Brian Gibler, MD)    

  11. Hypertension Management in Acute Neurovascular Emergencies
    (Arthur M. Pancioli, MD)    

  12. Advances in Acute Stroke Care
    (Brian A. Stettler, MD)    

  13. CME Post Test

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1 December 2008
H-FABP might be a novel biomarker for early AMI diagnosis
A proof-of-concept study suggestes heart fatty acid-binding protein (H-FABP) may be a promising new biomarker in patients with acute chest pain.
1 December 2008
Type 2 diabetics have a heightened response to glycoprotein (GP) IIb/IIIa inhibitors.
Type 2 diabetics have hyperactive platelets resulting in a hyperprocoagulant state and a heightened response to glycoprotein IIb/IIIa inhibitors.
25 November 2008
"Facilitated" PCI show better STEMI outcomes in real world setting
Researchers report that facilitated PCI is safe for STEMI patients facing a delay for PCI of 91 to 150 minutes.
25 November 2008
Early antiplatelet efficacy maintained over time
Research shows that the early inhibition of platelet aggregation achieved with clopidogrel and aspirin is maintained at 1 year in patients undergoing PCI.
25 November 2008
New anti-inflammatory compound shows promise for ACS
Researchers report that a novel anti-inflammatory compound, VIA-2291, shows promise in a phase 2 ACS trial.
20 November 2008
Re-assessment of antiplatelet use recommended for AMI bleeding patients
Physicians should reconsider the use of antiplatelet agents in AMI patients who develop bleeding.
18 November 2008
Early GPI Use provides short and long-term benefits for STEMI patients
Early administration of GPI in STEMI patients undergoing primary PCI resulted in significantly better 2-year clinical outcomes compared to GPI administration just prior to revascularization.
17 November 2008
Thrombolysis and aspirin are strongest predictors of in-hospital mortality in STEMI patients.
Out-of-hospital thrombolysis and aspirin therapy are the best predictors of in-hospital survival for STEMI patients.
12 November 2008
Early invasive management safe in NSTE ACS and improves outcomes in high-risk patients.
TIMACS investigators concluded that early invasive management is safe in patients with unstable angina or NSTEMI but overall has the same impact on the risk of death, new MI, or stroke compared with a delayed invasive strategy.
12 November 2008
New targets for TAFI inhibition reported
Researchers have uncovered new mechanisms and molecular targets for the inhibition of activated thrombin activatable fibrinolysis inhibitor (TAFIa).
11 November 2008
Increasing BMI shown to be inversely correlated with plasma levels of NTproBNP in CHF
Increasing BMI shown to be inversely correlated with plasma levels of NTproBNP in CHF even in patients matched for known influencing factors.
11 November 2008
Repeat scanning rates for CT pulmonary angiography increasing
At least one-third of ED patients undergoing first-time CT pulmonary angiography have a repeat scan within 5 years.
11 November 2008
New ACC-AHA Performance Measures Issued for AMI Care
The ACC/AHA have published newly revised performance measures to improve care for patients with AMI.
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