Emergency Medicine Cardiac Research and Education Group


CRUSADE National Quality Improvement Initiative

CRUSADE, a national quality improvement initiative, is designed to increase the practice of evidenced-based medicine for patients with diagnosed non-ST-segment-elevation acute coronary syndromes (NSTE ACS).

CRUSADE will use as its "gold standard", the NSTE ACS clinical practice guidelines developed by the American College of Cardiology (ACC) and the American Heart Association (AHA). Feedback to clinicians about care patterns and educational interventions will be used as strategies to improve the standard of care.

CRUSADE should raise physician awareness of and increase the application of the ACC/AHA guidelines for care of patients with acute coronary syndromes. Patients will benefit from this project.

For more information visit the CRUSADE website or send an email.


CARDIOVASCULAR AND NEUROVASCULAR EMERGENCIES: IMPLICATIONS FOR CLINICAL PRACTICE
Follow-up Monograph from the ACEP 2003 Symposium
(October 11, 2003, Boston, MA)
  1. Cover, Introduction and Table of Contents

  2. Pathophysiology of ACS
    (Brian Holroyd, MD)

  3. Updates in the Diagnosis of ACS in the ED: Symptoms, Markers, and ECGs
    (Deborah Diercks, MD)

  4. 2002 ACC/AHA Guidelines / CRUSADE Quality Improvement Initiative: Cardiologists And Emergency Physicians Working Together
    (E. Magnus Ohman, MD)

  5. Treatment of Non ST Elevation ACS with Antiplatelet Agents
    (James Hoekstra, MD)

  6. The Use of Clopidogrel for ACS: Clinical Implications of the CURE trial
    (Christopher Cannon, MD)

  7. When the Heart Fails: Identifying and Treating Heart Failure
    (Sean Collins, MD)

  8. Late Breaking Trial: The REDHOT Trial
    (Judd Hollander, MD)

  9. Putting the Pieces Together: Can we get Better with Hearts?
    (W. Brian Gibler, MD)

  10. How Do We Evaluate and Treat the Transient Ischemic Attack?
    (Arthur Pancioli, MD)

  11. Advances in the Diagnosis of Stroke: From Biomarkers to Neuroimaging
    (Edward Jauch, MD)

  12. CME POST TEST

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19 August 2008
Bivalirudin Equivalent to UFH but with less bleeding
ISAR-REACT 3 data reports that in low-risk patients undergoing PCI after clopidogrel preloading, bivalirudin was equivalent to UFH, but it did significantly reduce the incidence of major bleeding.
19 August 2008
Early tirofiban improves PCI outcomes in STEMI patients
On-TIME 2 results show that giving a pre-hospital high bolus dose of tirofiban to patients with an STEMI before PCI improves clinical outcome.
12 August 2008
CRUSADE data reports that medical records commonly incomplete.
Results from CRUSADE show that medical records of patients with NSTE ACS frequently lack important information like cardiac history, performance status, and a planned evidence-based medicine treatment approach.
12 August 2008
Positive troponin associated with higher mortality in unsuspected ACS detected by elective PCI.
About 6% of EVENT-registry elective-PCI patients had positive troponin tests prior to PCI and had greater than five times the one year mortality.
7 August 2008
An elevated BNP predictive of poor PE outcome.
High levels of BNP in pulmonary embolism patients indicated increased risk.
6 August 2008
Elevated cTn predicts PCI outcomes at 1-year.
Study reports that CAD patients with elevated cardiac troponin at the time of PCI are have increased morbidity and mortality over the following year.
6 August 2008
Improved TIMIT flow with PCI predicts ACS survival
German researchers reports that the TIMI flow rate achieved in patients with ACS treated with PCI predicts one year mortality.
6 August 2008
Testing and treatment delays impact on ADHF outcome
Researchers report that BNP level measurement delays and treating patients hospitalized with acute decompensated heart failure are strongly linked, and may impact on patient outcomes.
5 August 2008
HF hospitalizations continue to rise in the USA
The number of people hospitalized for heart failure in the USA has tripled since the late 1970s.
5 August 2008
Even minimal biomarker increases raise CVD death risk
Researchers report that even slight increases in two cardiac disease biomarkers raise the risk for CVD death in apparently healthy individuals.
5 August 2008
Eplerenone benefits in hypertensive AMI patients confirmed
EPHESUS investigators confirm the benefit of eplerenone was limited to reduced heart failure hospitalization in AMI without previous hypertension, but the drug improved all primary endpoints.
25 July 2008
OPTIMIZE-HF highlights mortality risk predictors
Data from OPTIMIZE report that factors like older age, low systolic blood pressure, and elevated heart rate and serum creatinine increase the risk for in-hospital death in heart failure.
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